EVERTON’S James McCarthy has joined fellow teammate Seamus Coleman as an injury concern ahead of Ireland's upcoming Euro 2016 qualifiers.
The midfielder did not travel with Roberto Martinez and the team to Russia for tonight’s Europa League game with Krasnodar.
Coleman was also left behind as expected, whilst he recovers from an injury.
Martinez remains hopeful that the pair could be involved in Sunday's Premier League fixture with Manchester United, but did indicate that if they are not, then the international period could be a beneficial time for recovery.
The Everton manager refused to rule them out of Irish duty for the games against Gibraltar and Germany, suggesting that the situation would have to be assessed at the weekend.
McCarthy’s situation appears to be more difficult, according to Martinez, as he has complained of tightness in his quad muscle and is struggling from fatigue.
"He has played a lot of football and he is feeling a bit fatigued," said Martinez. "It's not a real injury and I am not concerned by that.
"Seamus Coleman had concussion against Wolfsburg but then he suffered a little bit of a soft tissue problem. I don't think it will be too long (before he is fully fit). The international break should clear those injuries.
"Seamus and McCarthy have a chance with the Irish squad," he then explained. "James is a difficult one because of the games he's played. We will know more on Sunday but I have a very good relationship with the Irish association.
"Seamus could make Sunday, but it is early now to make a decision. James is similar; he finished against Liverpool very tired and cramping up, which might be a sign of a small injury."